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Genetic diversity of HLA system in two populations from Tamaulipas, Mexico: Ciudad Victoria and rural Tamaulipas. 2020
Tirzo Jesús Rodríguez-Munguía, and
Rodrigo Barquera, and
Carmen Adalid-Sáinz, and
Diana Iraíz Hernández-Zaragoza, and
Esteban Arrieta-Bolaños, and
Stephen Clayton, and
Guadalupe Aquino-Rubio, and
Marisela Del Rocío González-Martínez, and
Hanna Pacheco-Ubaldo, and
Liliana González-Medina, and
Abraham Lona-Sánchez, and
Alicia Bravo-Acevedo, and
Héctor Delgado-Aguirre, and
Néstor Escareño-Montiel, and
Yolanda Jaramillo-Rodríguez, and
Antonio Salgado-Adame, and
Federico Juárez-de la Cruz, and
Joaquín Zúñiga, and
Edmond J Yunis, and
Carolina Bekker-Méndez, and
Julio Granados
Molecular Biology Laboratory, Hospital General "Norberto Treviño Zapata", Dirección de Servicios de Salud de Tamaulipas, Ciudad Victoria, Tamaulipas, Mexico.
We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 148 Mexicans from the state of Tamaulipas living in Ciudad Victoria (N = 23) and rural communities (N = 125), to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haplotypes in the state of Tamaulipas include ten Native American, three European and one African haplotypes. Admixture estimates revealed that the main genetic components in the state of Tamaulipas are Native American (54.69 ± 0.93% by ML; 47.65% of Native American haplotypes) and European (34.66 ± 5.62% by ML; 33.56% of European haplotypes), and a relatively high African genetic component (10.65 ± 5.05% by ML; 12.42% of African haplotypes).
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Stephen Clayton, and
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Rodrigo Barquera, and
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Stephen Clayton, and
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Marisela Del Rocío González-Martínez, and
Hanna Pacheco-Ubaldo, and
Liliana González-Medina, and
Abraham Lona-Sánchez, and
Alicia Bravo-Acevedo, and
Héctor Delgado-Aguirre, and
Néstor Escareño-Montiel, and
Yolanda Jaramillo-Rodríguez, and
Antonio Salgado-Adame, and
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